新生儿听力缺失的危险因素
因素 | 备注 |
|---|---|
早产 | 新生儿重症监护病房（NICU）入院与风险增加约7倍相关† |
低阿普加评分 | <5（1分钟）或< 7-8（5分钟）‡ |
严重高胆红素血症和核黄疸 | 血清总胆红素≥35 mg/dL（≥598 μmol/L）或高于换血阈值≥10 mg/dL（≥171 μmol/L）†§ |
新生儿并发症 | 围产期缺氧或低氧症 长时间机械通气（≥5天）或需要辅助供氧 癫痫发作或呼吸暂停 |
先天性感染或其他疾病 | 寨卡病毒感染 |
Medications（药物应用史） | 氨基糖苷类 袢利尿剂（如呋塞米） 万古霉素 |
母体药物 | 氨基糖苷类 |
基因因素 | 导致高达80%的婴儿听力损失¶ |
Wroblewska-Seniuk KE, Dabrowski P, Szyfter W, Mazela J.Universal newborn hearing screening: methods and results, obstacles, and benefits. Pediatr Res.2017;81(3):415-422.doi:10.1038/pr.2016.250. †Davis BE, Leppert MO, German K, et al.Primary Care Framework to Monitor Preterm Infants for Neurodevelopmental Outcomes in Early Childhood. Pediatrics.2023;152(1):e2023062511.doi:10.1542/peds.2023-062511 ‡Kvestad E, Lie KK, Eskild A, Engdahl B.Sensorineural hearing loss in children: the association with Apgar score.A registry-based study of 392,371 children in Norway. Int J Pediatr Otorhinolaryngol.2014;78(11):1940-1944.doi:10.1016/j.ijporl.2014.08.032 §Wickremasinghe AC, Risley RJ, Kuzniewicz MW, et al.Risk of Sensorineural Hearing Loss and Bilirubin Exchange Transfusion Thresholds. Pediatrics.2015;136(3):505-512.doi:10.1542/peds.2014-3357 ¶ Choe G, Park SK, Kim BJ.Hearing loss in neonates and infants. Clin Exp Pediatr.2023;66(9):369-376.doi:10.3345/cep.2022.01011 | |
